Back

FUNCTIONAL DIAGNOSTICS

Why Retesting Every 90 Days Matters More Than You Think

Why Retesting Every 90 Days Matters More Than You Think

Jan 14, 2026

If you’re only testing your labs once a year, you’re not optimizing - you’re guessing.

That once-a-year checkup might be enough to catch disease, but it’s useless if your goal is to improve how you look, feel, and perform. Health is dynamic. Hormones fluctuate. Habits shift. Protocols need to be dialed in.

That’s why at Catalyst, we retest every 90 days. Here's why it matters, and what it lets us do that no other model can.

Health Is a Moving Target

Your body is not a fixed machine. It’s a constantly adapting system.
Every quarter, you’re affected by:

  • Seasons: Less sunlight in winter impacts Vitamin D, mood, and testosterone

  • Training cycles: Shifting your workout focus changes nutrient and hormone demands

  • Stress & sleep: Cortisol and inflammation markers respond fast to life circumstances

  • Protocol changes: New supplements, medications, or interventions all need re-evaluation

Waiting a full year to check in means you’re flying blind for 9+ months, while your biology moves on without you.

Your Hormones Don’t Stay Static

Even with stable therapy or great lifestyle habits, hormone levels fluctuate.

  • Testosterone can drift based on stress, sleep, travel, or even dietary shifts

  • Estradiol can spike if testosterone converts too quickly (affecting mood and libido)

  • SHBG and DHT can shift your free testosterone, even if total looks the same

  • Cortisol rhythms can become dysregulated due to overtraining or burnout

Quarterly testing catches these trends early, before symptoms creep back in - and lets us fine-tune your protocol, not just “wait and see.”

Biomarker Feedback Drives Accountability

There’s a psychological shift that happens when you know you’re retesting soon.

  • You stay more engaged in your habits

  • You treat nutrition, training, and recovery more seriously

  • You get rewarded with visible data that validates your efforts, or flags where you’re slipping

In other words, it keeps health from becoming an abstract idea and grounds it in real, trackable progress.

Optimization Requires Iteration

No protocol is perfect out of the gate. The first 90 days are just the starting point.

Quarterly retesting lets us:

  • Validate what’s working and double down

  • Spot early signs of imbalance before symptoms return

  • Adjust dosages, timing, or formulations based on how your body responds

  • Catch unintended consequences (e.g., elevated hematocrit on TRT, estrogen swings, nutrient depletion)

  • Track performance metrics tied to your goals: strength, libido, sleep, focus, body comp

This is what turns “treatment” into tuning.

What We Track Every 90 Days

Each retest is targeted to your protocol and priorities, but typically includes:

  • Hormone panel: Total/Free T, Estradiol, SHBG, DHEA-S, LH/FSH

  • Metabolic markers: Insulin, glucose, A1c, lipid panel

  • Inflammation & recovery: hs-CRP, ESR

  • Nutrient status: B12, folate, Vitamin D

  • Specialty markers as needed (hematocrit, thyroid, cortisol, IGF-1, etc.)

We don't just hand you results - we translate them into action.

The Bottom Line

Retesting every 90 days isn't excessive, it’s essential. Retesting helps to:

  • Catch problems early

  • Track progress over time

  • Keep your protocol on-target

  • Put you in a feedback loop that compounds results

At Catalyst, we don’t “set it and forget it.”
We measure, iterate, and improve - every 90 days.

Because the goal isn’t just normal. The goal is better.

Book an appointment

Book an appointment

Read more posts

Read more posts

New Preclinical Research Suggests Alzheimer's Disease May Be Reversible

The Catalyst Approach to Perimenopause: Personalized, Not Patchwork

What Happens to Estrogen, Progesterone, and Testosterone After 40?

​​What Makes a Good Functional Medicine Doctor?